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Oxidative stress has been shown to upregulate NKG2D ligands, including MICA and ULBP, which may trigger the collapse of hair follicle immune privilege (HF-IP) and contribute to the development of alopecia areata (4)

In short, a drug acting on the gut changed the brain's stress response

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Here, ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was used to determine the concentration of LC and ALC in the serum of healthy controls and patients with MDD