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(Science-Based Medicine) Potential thyroid, kidney or metabolic disturbances some anecdotal reports and reviews raise these as possible but under-studied risks

If any unexpected reactions occur, discontinue use and seek medical guidance

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In U87 and T98G cells treated with metformin and simvastatin, there was a significant downregulation in the expression of the mature form of SREBP2, MBTPS1, and SCAP