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Many insurance reviewers look for evidence of "structured lifestyle intervention" rather than vague statements about "trying to eat better." Specific caloric goals, meal plans, and exercise logs demonstrate the level of effort that Anthem expects to see before approving GLP-1 therapy

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DLima DD, Hashimoto S, Chen PC, et al

They're more likely to result in side effects such as cramping, gas and bloating, so doctors usually don't recommend them for daily use

Drug Interactions The concomitant use of SYNJARDY or SYNJARDY XR with specific drugs may increase the risk of metformin-associated lactic acidosis: those that impair renal function, result in significant hemodynamic change, interfere with acid-base balance or increase metformin accumulation [see DRUG INTERACTIONS ]