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However, L-CN inhibits the accumulation of neutrophil protein kinase C receptor 36 , and supplementation with L-CN reduces the postoperative neutrophillymphocyte ratio in the short term 37

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Pregnancy and breastfeeding Small clinical studies suggest that ALA may be safe during pregnancy at doses up to 600mg/day for several weeks, with no serious adverse effects reported.40 However, larger, long-term studies are lacking, and there is no reliable safety data for breastfeeding

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