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A study on the long term effect of semaglutide demonstrated that individuals who engaged in regular physical activity while on semaglutide experienced greater weight loss (up to 20%) compared to those who did not exercise

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There may be some evidence, though questionable, that active ingredients like berberine and green tea might curb cravings and reduce appetite a bit , but the effects are not dramatic enough for this to be an FDA-approved strategy. In other words, the patches are likely much ado about nothing