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First, the detailed mechanisms of ferroptosis have been specifically investigated for cell death caused by erastin and other RSLs in NRAS mutant HT-1080 fibrosarcoma and related cancer cell lines, as well as for glutamate-induced cell death in brain slices

This clinically justified approach resulted in a selection bias, with only 90 positive cases (90/983) among 983 eligible patients, yielding a distribution ratio of 1:9.2

Rosenfeld M, & Ladiges W

Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells

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