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Schroder, S., Hoch, W., Becker, C

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Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer's disease

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The first step in the process involves the enzyme tyrosine hydroxylase which, like phenylalanine hydroxylase (of tyrosine synthesis), requires tetrahydrobiopterin (BH 4 , or also written H 4 B) as a cofactor